SCHEMBL20788948

SCHEMBL20788948

Cc1cccc(N2c3ccccc3N(C)c3ccccc32)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.52
MGLL Q99685 1/20 0.52
L3MBTL1 Q9Y468 3/20 0.50
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
CASP6 P55212 1/20 0.43
MAPT P10636 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ACHE P22303 1/20 0.41
MAOA P21397 1/20 0.41
KCNH2 Q12809 2/20 0.41
ADRB1 P08588 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20789095 0.88 HSP90AA1 (0.55) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL25802442 0.84 MAOA (0.43) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL12841526 0.81 OPRK1 (0.40) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL10072419 0.81 OPRK1 (0.43) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL18054953 0.79 HSP90AA1 (0.55) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL12251824 0.79 MAOA (0.44) MGLLL3MBTL1KMT2AMEN1GAA
SCHEMBL13651337 0.78 MEN1 (0.55) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL16945820 0.78 HSP90AA1 (0.49) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL16945821 0.78 HSP90AA1 (0.49) HSP90AA1MGLLL3MBTL1KMT2AMEN1
SCHEMBL16945822 0.78 BCHE (0.53) HSP90AA1MGLLL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10770661-B2 Thermally activated delayed fluorescence material and application thereof in organic electroluminescence device KUNSHAN GP-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2020-09-08 US disclosed
US-20190221375-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND OXIDE SEMICONDUCTOR ELECTRODE FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed
US-20190074447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENCE DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2019-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190074447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENCE DEVICE KCNH1, KCNH2, KCNH3 HSP90AA1 2303/4885MGLL 3816/4885L3MBTL1 1355/4885
US-10770661-B2 Thermally activated delayed fluorescence material and application thereof in organic electroluminescence device KCNH1, KCNH2, KCNH3 HSP90AA1 2303/4885MGLL 3816/4885L3MBTL1 1355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.