Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25806761 | 0.88 | LMNA (0.34) | FGFR1SRCMEN1KMT2AKDM4E | |
| SCHEMBL21988764 | 0.86 | FGFR1 (0.33) | FGFR1SRCMEN1KMT2AKDM4E | |
| SCHEMBL22044813 | 0.84 | KCNH2 (0.33) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL22045264 | 0.82 | FGFR1 (0.32) | FGFR1KDM4EALDH1A1 | |
| SCHEMBL25510737 | 0.73 | BRD4 (0.34) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL25806767 | 0.72 | F2RL1 (0.33) | FGFR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25806765 | 0.70 | FGFR1 (0.33) | FGFR1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21988814 | 0.70 | F2RL1 (0.32) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL25808546 | 0.70 | KCNH2 (0.65) | — | |
| SCHEMBL21988852 | 0.69 | BRD4 (0.33) | FGFR1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | FGFR1 3286/4885SRC 1646/4885MEN1 3178/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | FGFR1 3286/4885SRC 1646/4885MEN1 3178/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | FGFR1 3286/4885SRC 1646/4885MEN1 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.