Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24212088 | 0.74 | HRH3 (0.36) | GRIN2BGRIN1S1PR5PRMT5WDR77 | |
| SCHEMBL22051948 | 0.72 | GRIN2B (0.38) | GRIN2BGRIN1OPRK1S1PR5 | |
| SCHEMBL22051944 | 0.71 | KMT2A (0.41) | IGF1RGRIN2B | |
| SCHEMBL22051947 | 0.70 | PLAU (0.40) | GRIN2BGRIN1S1PR5CYP2C9KCNH2 | |
| SCHEMBL22050850 | 0.66 | TP53 (0.44) | CYP2C9 | |
| SCHEMBL22051360 | 0.65 | GRIN2B (0.36) | GRIN2BGRIN1S1PR5CYP2C9KCNH2 | |
| SCHEMBL2277272 | 0.63 | MGLL (0.46) | OPRK1S1PR5SPHK2SPHK1 | |
| SCHEMBL2277268 | 0.63 | MGLL (0.46) | OPRK1S1PR5SPHK2SPHK1 | |
| SCHEMBL2277277 | 0.63 | MGLL (0.46) | OPRK1S1PR5SPHK2SPHK1 | |
| SCHEMBL1687453 | 0.60 | MAOB (0.64) | OPRK1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |