Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051956 | 0.83 | MAPT (0.45) | ALDH1A1MAPTKDM4EHPGDCYP2C19 | |
| SCHEMBL22050825 | 0.75 | MAPT (0.50) | ALDH1A1MAPTCYP2C19POLBHTT | |
| SCHEMBL22051934 | 0.74 | S1PR5 (0.39) | S1PR2SOS1S1PR5KCNH2 | |
| SCHEMBL24212088 | 0.73 | HRH3 (0.36) | GRIN2BGRIN1HRH3S1PR5CYP2C9 | |
| SCHEMBL23888890 | 0.73 | LMNA (0.35) | HPGD | |
| SCHEMBL22051947 | 0.73 | PLAU (0.40) | GRIN2BALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL22051357 | 0.72 | MAPT (0.42) | GRIN2BALDH1A1MAPTCYP2C19POLB | |
| SCHEMBL22051948 | 0.71 | GRIN2B (0.38) | GRIN2BALDH1A1GRIN1POLBHTT | |
| SCHEMBL23888904 | 0.71 | ICMT (0.34) | GRIN2BPOLB | |
| SCHEMBL22050495 | 0.71 | GAA (0.44) | GRIN2BALDH1A1MAPTCYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |