Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051947 | 0.88 | PLAU (0.40) | GRIN2BSLC6A7GRIN1POLBHTT | |
| SCHEMBL22051362 | 0.81 | TP53 (0.46) | GRIN2BPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL22051934 | 0.73 | S1PR5 (0.39) | SLC6A7KMT2AS1PR5 | |
| SCHEMBL22051950 | 0.72 | IGF1R (0.37) | GRIN2BGRIN1S1PR5OPRK1 | |
| SCHEMBL22051360 | 0.71 | GRIN2B (0.36) | GRIN2BGRIN1POLBHTTALDH1A1 | |
| SCHEMBL22050501 | 0.71 | TP53 (0.49) | GRIN2BSLC6A7POLBALDH1A1KMT2A | |
| SCHEMBL22051968 | 0.70 | TP53 (0.47) | GRIN2BSLC6A7POLBHTTALDH1A1 | |
| SCHEMBL22051970 | 0.69 | KIF11 (0.40) | GRIN2BSLC6A7GRIN1KMT2AMEN1 | |
| SCHEMBL22050847 | 0.69 | TP53 (0.46) | POLBALDH1A1KMT2AMEN1PLG | |
| SCHEMBL22050494 | 0.69 | TRIM24 (0.41) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |