Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22821490 | 0.74 | CYP19A1 (0.46) | SMN1; SMN2TSHRKDM4EMEN1ALDH1A1 | |
| SCHEMBL22052185 | 0.73 | MAPK1 (0.47) | EGFRERBB2DDAH1CYP2C9SMN1; SMN2 | |
| SCHEMBL4124111 | 0.72 | DDAH1 (0.65) | DDAH1CYP1A2CYP2C9SMN1; SMN2TSHR | |
| SCHEMBL32670361 | 0.71 | CYP19A1 (0.43) | SMN1; SMN2TSHRMEN1LMNAKMT2A | |
| SCHEMBL13036563 | 0.70 | CYP19A1 (0.47) | TSHRLMNAKMT2ANPC1RAB9A | |
| SCHEMBL10761755 | 0.70 | DDAH1 (0.61) | DDAH1CYP1A2CYP2C9TSHRLMNA | |
| SCHEMBL19651813 | 0.70 | DDAH1 (0.61) | DDAH1CYP1A2CYP2C9SMN1; SMN2TSHR | |
| SCHEMBL4619198 | 0.70 | DDAH1 (0.61) | DDAH1CYP1A2CYP2C9SMN1; SMN2KDM4E | |
| SCHEMBL10946704 | 0.68 | CYP1A2 (0.74) | DDAH1CYP1A2CYP2C9SMN1; SMN2KDM4E | |
| SCHEMBL26156421 | 0.68 | CYP19A1 (0.45) | SMN1; SMN2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230147312-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN | GLYCOMIMETICS, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20200171005-A9 | Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker | GLYCOMIMETICS, INC. (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200171005-A9 | Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker | SELE, SELP, SELPLG | EGFR 2044/4885ERBB2 1752/4885DDAH1 520/4885 |
| US-20230147312-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND RELATED CONDITIONS WITH ANTAGONISTS OF E-SELECTIN | SELP, SELE, SELPLG | EGFR 1035/4885ERBB2 1625/4885DDAH1 1231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.