Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32670361 | 0.83 | CYP19A1 (0.43) | CYP19A1NPC1RAB9ATSHRLMNA | |
| SCHEMBL13036563 | 0.82 | CYP19A1 (0.47) | CYP19A1NPC1RAB9ATSHRLMNA | |
| SCHEMBL21991877 | 0.82 | CHRNB2 (0.43) | LMNAMAPTALOX15MEN1KMT2A | |
| SCHEMBL26156421 | 0.79 | CYP19A1 (0.45) | CYP19A1NPC1RAB9ATSHRLMNA | |
| SCHEMBL19326596 | 0.78 | CYP19A1 (0.42) | CYP19A1NPC1RAB9ATSHRLMNA | |
| SCHEMBL30788969 | 0.77 | XDH (0.43) | CYP19A1NPC1RAB9ASMN1; SMN2GGPS1 | |
| SCHEMBL22821501 | 0.76 | LGALS3 (0.38) | — | |
| SCHEMBL21669923 | 0.76 | HDAC3 (0.45) | RAB9ATSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30788869 | 0.76 | PTGS2 (0.43) | CYP19A1NPC1RAB9ATSHRLMNA | |
| SCHEMBL20995389 | 0.75 | CYP19A1 (0.47) | CYP19A1NPC1RAB9ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548908-B2 | Heterobifunctional inhibitors of E-selectin and galectin-3 | GLYCOMIMETICS, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20200399301-A1 | HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTIN AND GALECTIN-3 | GLYCOMIMETICS, INC. (US) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399301-A1 | HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTIN AND GALECTIN-3 | LGALS3, LGALS3BP, LGALS1 | CYP19A1 4874/4885NPC1 2287/4885RAB9A 2221/4885 |
| US-11548908-B2 | Heterobifunctional inhibitors of E-selectin and galectin-3 | LGALS3, LGALS3BP, LGALS1 | CYP19A1 4874/4885NPC1 2287/4885RAB9A 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.