Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705109 | 0.70 | KDM4E (0.46) | MTNR1AMTNR1BCYP3A4PDE4APDE4B | |
| SCHEMBL7684229 | 0.69 | TAAR1 (0.44) | TAAR1CYP3A4STING1HTR2APTGS2 | |
| SCHEMBL455446 | 0.69 | TAAR1 (0.44) | TAAR1CYP3A4HTR2APDE4APDE4B | |
| SCHEMBL5885507 | 0.67 | KDM4E (0.46) | CYP3A4KDM4E | |
| SCHEMBL28066598 | 0.67 | TAAR1 (0.43) | TAAR1CYP3A4HTR2APTGS2KDM4E | |
| SCHEMBL5907891 | 0.67 | MTNR1A (0.45) | MTNR1AMTNR1BCYP3A4KDM4E | |
| SCHEMBL10367375 | 0.66 | MAPT (0.43) | MTNR1AMTNR1BCYP3A4KDM4E | |
| SCHEMBL1096751 | 0.66 | MTNR1A (0.38) | MTNR1AMTNR1BSTING1KDM4E | |
| SCHEMBL3066721 | 0.65 | CA12 (0.44) | — | |
| SCHEMBL4518140 | 0.65 | GABRA1 (0.43) | MTNR1AMTNR1BCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | claimed |
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | claimed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| EP-1670772-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030736-A1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | MTNR1A 1180/4885MTNR1B 1054/4885TAAR1 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.