Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354613 | 0.81 | MAPT (0.43) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL22187002 | 0.78 | MAPT (0.41) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL5888919 | 0.73 | HPRT1 (0.48) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL1814529 | 0.73 | ALOX5 (0.48) | ATMCYP3A4ALDH1A1CYP2A6HSD17B10 | |
| SCHEMBL5670529 | 0.73 | DHFR (0.42) | MAPTRAB9ASMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL23129247 | 0.72 | SLC22A12 (0.51) | MAPTLMNAATMALDH1A1TSHR | |
| SCHEMBL13915445 | 0.70 | ATM (0.56) | ATMCYP3A4ALDH1A1CYP2A6EGFR | |
| SCHEMBL12262993 | 0.70 | ALDH1A1 (0.45) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL31656347 | 0.69 | DNMT1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12263058 | 0.69 | ALDH1A1 (0.44) | MAPTATMCYP3A4ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |