Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 6/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20151012 | 0.80 | NPC1 (0.37) | — | |
| SCHEMBL23570956 | 0.80 | HSD17B2 (0.40) | HSD17B2HSD17B1FFAR1AOC3BTK | |
| SCHEMBL22053528 | 0.78 | FAAH (0.40) | — | |
| SCHEMBL22478905 | 0.77 | MEN1 (0.35) | HSD17B2HSD17B1 | |
| SCHEMBL20151009 | 0.72 | SIGMAR1 (0.49) | — | |
| SCHEMBL19130293 | 0.69 | KMO (0.34) | — | |
| SCHEMBL20942015 | 0.69 | HSD17B2 (0.36) | HSD17B2HSD17B1FFAR1AOC3 | |
| SCHEMBL21861794 | 0.68 | HSD17B1 (0.45) | HSD17B2HSD17B1AOC3 | |
| SCHEMBL20151005 | 0.68 | MEN1 (0.30) | — | |
| SCHEMBL23543822 | 0.68 | HSD17B2 (0.39) | HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225071-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | WO | disclosed |