Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.45 |
| ▸ | MMP2 | P08253 | 6/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054417 | 1.00 | POLB (0.49) | POLBNPSR1MMEALDH1A1ASAH1 | |
| SCHEMBL23171829 | 0.83 | POLB (0.54) | POLBNPSR1MMEALDH1A1ASAH1 | |
| SCHEMBL24105903 | 0.76 | POLB (0.57) | POLBNPSR1MMEALDH1A1NAAA | |
| SCHEMBL8650962 | 0.74 | MMP2 (0.42) | POLBNPSR1MMEASAH1NAAA | |
| SCHEMBL8649894 | 0.74 | MMP2 (0.42) | POLBNPSR1MMEASAH1NAAA | |
| SCHEMBL7077499 | 0.74 | MME (0.56) | POLBMMEALDH1A1ASAH1ACER2 | |
| SCHEMBL7313784 | 0.73 | POLB (0.55) | POLBNPSR1MMENAAACNR2 | |
| SCHEMBL7313780 | 0.73 | POLB (0.55) | POLBNPSR1MMENAAACNR2 | |
| SCHEMBL6818316 | 0.73 | POLB (0.45) | POLBNPSR1MMEALDH1A1ASAH1 | |
| SCHEMBL2698411 | 0.72 | POLB (0.69) | POLBALDH1A1ASAH1ACER2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020107078-A1 | DENDRIMER FOR THERAPY AND IMAGING | STARPHARMA PTY LTD (AU) | 2020-06-04 | — | — | WO | disclosed |