Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.51 |
| ▸ | DPP4 | P27487 | 3/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313784 | 1.00 | POLB (0.55) | POLBNPSR1DPP7DPP8DPP9 | |
| SCHEMBL7375880 | 0.86 | OPRM1 (0.51) | POLBNPSR1DPP7CNR2TSHR | |
| SCHEMBL24512887 | 0.85 | LMNA (0.45) | NPSR1DPP8DPP9DPP4CNR2 | |
| SCHEMBL13598088 | 0.85 | MMP2 (0.56) | DPP7DPP8DPP9LMNA | |
| SCHEMBL11518823 | 0.85 | MMP2 (0.56) | DPP7DPP8DPP9LMNA | |
| SCHEMBL24105903 | 0.84 | POLB (0.57) | POLBNPSR1MMECNR2TSHR | |
| SCHEMBL23052552 | 0.84 | HTR2A (0.51) | NPSR1CNR2LMNATSHRXIAP | |
| SCHEMBL7307439 | 0.84 | CTSC (0.55) | POLBNPSR1LMNATSHRXIAP | |
| SCHEMBL7307442 | 0.84 | CTSC (0.55) | POLBNPSR1LMNATSHRXIAP | |
| SCHEMBL11104392 | 0.81 | DPP4 (0.50) | NPSR1DPP8DPP9DPP4SLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |