Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1449524 | 0.84 | HPGD (0.66) | HPGDRAB9AMAPTMGAMAMY1A | |
| SCHEMBL2205869 | 0.73 | LMNA (0.47) | RAB9ANPC1L3MBTL1MAPTMGAM | |
| SCHEMBL3363237 | 0.71 | MGAM (0.45) | HPGDRAB9ANPC1MGAMAMY1A | |
| SCHEMBL4023150 | 0.70 | SMN1; SMN2 (0.47) | HPGDRAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL14267025 | 0.70 | GAA (0.43) | HPGDRAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL2204928 | 0.69 | HTT (0.54) | RAB9ANPC1L3MBTL1MAPTGSK3B | |
| SCHEMBL23209625 | 0.69 | RAB9A (0.49) | HPGDRAB9ANPC1MAPTMGAM | |
| SCHEMBL1753283 | 0.67 | RAB9A (0.85) | HPGDRAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL9667197 | 0.67 | NPC1 (0.50) | HPGDRAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL4860671 | 0.67 | RAB9A (0.54) | HPGDRAB9ANPC1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670772-B1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2011-08-17 | — | — | EP | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7345009-B2 | Reacting 4-phenyl pyraoline compound with phenyl isocyanate compound | BAYER CROPSCIENCE AG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | MAURER FRITZ | 2008-03-13 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| CN-1646521-A | Substituted 4-heteroarylpyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | CN | disclosed |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | BAYER CROPSCIENCE AG (DE) | 2005-06-02 | — | — | US | disclosed |
| EP-1474418-A1 | SUBSTITUTED 4-HETARYL-PYRAZOLINES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066625-A1 | SUBSTITUTED 4-HETARYL-PYRAZOLINES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064732-A1 | Substituted 4-hetarylpyrazolines | CYP4F3, CYP4X1, CYP4B1 | HPGD 2160/4885RAB9A 363/4885NPC1 2611/4885 |
| US-20050119128-A1 | Substituted 4-hetaryl-pyrazolines as pest control agents | CYP4X1, CYP4F3, DDT | HPGD 2445/4885RAB9A 235/4885NPC1 3726/4885 |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | HPGD 818/4885RAB9A 1773/4885NPC1 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.