Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | ADH1B | P00325 | 3/20 | 0.43 |
| ▸ | ADH1A | P07327 | 3/20 | 0.43 |
| ▸ | ADH7 | P40394 | 3/20 | 0.43 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500002 | 0.84 | CASP2 (0.57) | CASP2NAAALPAR1HPGDGBA1 | |
| SCHEMBL22242831 | 0.82 | CASP2 (0.66) | CASP2ADH1BADH1AADH7ADH1C | |
| SCHEMBL20220317 | 0.81 | MEN1 (0.50) | CASP2ADH1BADH1AADH7ADH1C | |
| SCHEMBL5501191 | 0.79 | FAAH (0.50) | CASP2NAAALPAR1HPGDEPHX2 | |
| SCHEMBL22134304 | 0.78 | CASP2 (0.59) | CASP2ADH1BADH1AADH7ADH1C | |
| SCHEMBL5505706 | 0.77 | FAAH (0.58) | CASP2NAAALPAR1HPGDEPHX2 | |
| SCHEMBL22056571 | 0.76 | EPHX1 (0.60) | CASP2ADH1BADH1AADH7ADH1C | |
| SCHEMBL5500554 | 0.76 | FAAH (0.61) | CASP2NAAALPAR1HPGDEPHX2 | |
| SCHEMBL5495525 | 0.76 | FAAH (0.61) | CASP2NAAALPAR1HPGDEPHX2 | |
| SCHEMBL6803183 | 0.73 | FAAH (0.53) | CASP2ADH1BADH1AADH7ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |