Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687263 | 0.82 | RIPK1 (0.37) | FAAHMCL1CNR1KMT2AALDH1A1 | |
| SCHEMBL17680252 | 0.79 | FAAH (0.42) | FAAHMCL1EPHX2KMT2AALDH1A1 | |
| SCHEMBL621056 | 0.78 | KDM4C (0.44) | MCL1CNR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12565693 | 0.76 | CNR1 (0.46) | CNR1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL618269 | 0.75 | EPHX1 (0.50) | NAAACNR1EPHX1 | |
| SCHEMBL29306578 | 0.73 | EPHX1 (0.58) | NAAACNR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9499386 | 0.72 | CNR1 (0.34) | CNR1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24883639 | 0.72 | RIPK1 (0.42) | CNR1KMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12424179 | 0.71 | FAAH (0.50) | FAAHMCL1NAAAEPHX2KMT2A | |
| SCHEMBL12673154 | 0.71 | KMT2A (0.58) | FAAHMCL1NAAAEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |