SCHEMBL28527403

SCHEMBL28527403

CC(C)(C)[Si](C)(C)OC1CCc2cc[c]cc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7197862 0.89 IDO1 (0.31) IDO1
SCHEMBL22056586 0.79 IDO1 (0.53) IDO1
SCHEMBL432585 0.76
SCHEMBL20270050 0.75 HTR2A (0.43) IDO1
SCHEMBL20269757 0.72 ALDH1A1 (0.31)
SCHEMBL1895008 0.72 STS (0.33)
SCHEMBL227332 0.71 SLC6A4 (0.41) IDO1
SCHEMBL29700361 0.71 LRRK2 (0.48)
SCHEMBL814820 0.69 PDPK1 (0.33)
SCHEMBL1451592 0.68 IDO1 (0.40) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108112251-B NRF2 modulators 葛兰素史克知识产权发展有限公司 2021-03-05 CN disclosed