SCHEMBL22057481

SCHEMBL22057481

CC1(C)c2ccccc2-c2cc3c(cc21)oc1cc(Br)ccc13

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.36
PDK2 Q15119 1/20 0.35
ALK Q9UM73 1/20 0.34
MEN1 O00255 3/20 0.33
MAPT P10636 3/20 0.33
KMT2A Q03164 3/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
MAOA P21397 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22058506 0.96 PDK2 (0.36) PGRPDK2ALKMEN1MAPT
SCHEMBL22057708 0.92 GABRP (0.39) PGRPDK2MEN1MAPTKMT2A
SCHEMBL22057707 0.87 GABRP (0.40) PGRPDK2MEN1MAPTKMT2A
SCHEMBL19195567 0.86 PGR (0.44) PGRPDK2ALKMEN1MAPT
SCHEMBL19152007 0.86 PDK2 (0.35) PGRPDK2ALKMEN1MAPT
SCHEMBL802502 0.85 PGR (0.48) PGRMEN1MAPTKMT2AKDM4E
SCHEMBL20023628 0.82 PGR (0.42) PGRPDK2ALKMEN1MAPT
SCHEMBL18563483 0.81 MEN1 (0.46) PGRMEN1MAPTKMT2AKDM4E
SCHEMBL14643277 0.80 PDK2 (0.39) PDK2ALKMEN1MAPTKMT2A
SCHEMBL19297317 0.80 PGR (0.43) PGRMEN1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200227644-A1 ORGANIC LIGHT-EMITTING DIODE OPERABLE AT LOW VOLTAGE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2020-07-16 US disclosed
EP-3660934-A1 ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS SFC Co., Ltd. (KR) 2020-06-03 EP disclosed