SCHEMBL14643277

SCHEMBL14643277

CC1(C)c2ccccc2-c2cc3c4ccccc4c4cc(Br)ccc4c3cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
RXFP1 Q9HBX9 1/20 0.35
OPRM1 P35372 2/20 0.32
MLNR O43193 1/20 0.32
NR1I2 O75469 1/20 0.32
CHRM2 P08172 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
CHRM3 P20309 1/20 0.32
DRD1 P21728 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2793639 0.89 PDK2 (0.38) PDK2OPRM1MLNRNR1I2CHRM2
SCHEMBL17789546 0.89 PDE4B (0.35) PDK2MEN1KMT2ARXFP1ALK
SCHEMBL15705966 0.89 PDK2 (0.41) PDK2MEN1KMT2ARXFP1PTPRC
SCHEMBL20011331 0.88 HTR2A (0.38) PDK2MEN1KMT2AOPRM1MLNR
SCHEMBL15801398 0.87 PDK2 (0.41) PDK2MEN1KMT2ARXFP1ALK
SCHEMBL2382542 0.86 MEN1 (0.36) PDK2MEN1KMT2ARXFP1ALDH1A1
SCHEMBL2380626 0.84 DPP4 (0.36) PDK2MEN1KMT2ARXFP1ALK
SCHEMBL2380288 0.84 PDK2 (0.33) PDK2MEN1KMT2ARXFP1ALK
SCHEMBL2380862 0.83 PDK2 (0.37) PDK2ALKPTPRCRXRA
SCHEMBL15763798 0.83 PDK2 (0.38) PDK2PTPRCCA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428269-B2 Indenotriphenylene derivative and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-10-01 US disclosed
US-9929351-B2 Indenotriphenylene-based amine derivative for organic electroluminescent device NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2018-03-27 US disclosed
US-20160240784-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2016-08-18 US disclosed
US-20160240784-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2016-08-18 US disclosed
US-20160218293-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-07-28 US disclosed
US-20160218293-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-07-28 US disclosed
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-06-30 US disclosed
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-06-30 US disclosed
US-20150255731-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-09-10 US disclosed
US-20150255731-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-09-10 US disclosed
WO-2013009079-A1 TRIPHENYLENE-BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE USING SAME 주식회사 두산 (KR) 2013-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240784-A1 INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE FOR ORGANIC ELECTROLUMINESCENT DEVICE AHR, MLLT1, AR PDK2 2896/4885MEN1 3430/4885KMT2A 745/4885
US-10428269-B2 Indenotriphenylene derivative and organic electroluminescence device using the same ICMT, INCENP, ITPA PDK2 1255/4885MEN1 2750/4885KMT2A 3084/4885
US-20160218293-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE ORAI2, TRPC6, ICMT PDK2 1423/4885MEN1 1885/4885KMT2A 1737/4885
US-20160190470-A1 ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME EBPL, ICMT, ICOSLG PDK2 976/4885MEN1 3325/4885KMT2A 2387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.