Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821806 | 0.93 | CYP3A4 (0.54) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21794939 | 0.87 | KCNA5 (0.49) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821609 | 0.85 | MAP1LC3B (0.48) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821560 | 0.84 | MAP1LC3B (0.46) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821876 | 0.84 | MAP1LC3B (0.43) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821705 | 0.84 | MAP1LC3B (0.43) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21795151 | 0.83 | MAPT (0.43) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821996 | 0.83 | MAP1LC3B (0.46) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821814 | 0.82 | MAP1LC3B (0.45) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL21821987 | 0.82 | CYP2C9 (0.42) | MAP1LC3BCYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529321-B2 | Use of aminomethylenecyclohexane-1,3-dione compound | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2022-12-20 | — | — | US | disclosed |
| US-20200170966-A1 | USE OF AMINOMETHYLENECYCLOHEXANE-1,3-DIONE COMPOUND | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200170966-A1 | USE OF AMINOMETHYLENECYCLOHEXANE-1,3-DIONE COMPOUND | ATG7, BECN1, SQSTM1 | MAP1LC3B 10/4885CYP3A4 4623/4885CYP2C9 4737/4885 |
| US-11529321-B2 | Use of aminomethylenecyclohexane-1,3-dione compound | ATG7, BECN1, SQSTM1 | MAP1LC3B 10/4885CYP3A4 4623/4885CYP2C9 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.