SCHEMBL22057751

SCHEMBL22057751

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5c(ccc6ccc7c8ccccc8oc7c65)c4)c3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.39
▸ MAPT P10636 8/20 0.38
▸ ALDH1A1 P00352 4/20 0.37
▸ TSHR P16473 3/20 0.37
▸ KDM4E B2RXH2 3/20 0.37
▸ POLB P06746 2/20 0.37
▸ HPGD P15428 1/20 0.37
▸ PLA2G2A P14555 2/20 0.37
▸ PLA2G4A P47712 2/20 0.37
▸ PLA2G10 O15496 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ LMNA P02545 4/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ USP2 O75604 1/20 0.36
▸ JAK2 O60674 1/20 0.36
▸ ZAP70 P43403 1/20 0.36
▸ SYK P43405 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ HCRTR1 O43613 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24275450 0.96 ALOX5 (0.38) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24274815 0.94 ALOX5 (0.38) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24274809 0.92 MAPT (0.39) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24275041 0.91 MAPT (0.39) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL22879988 0.91 ALOX5 (0.41) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24275125 0.91 ALOX5 (0.43) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24275136 0.90 ALDH1A1 (0.38) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24275046 0.90 MAPT (0.38) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL24275371 0.90 MAPT (0.39) ALOX5MAPTALDH1A1TSHRKDM4E
SCHEMBL23134249 0.90 PLA2G2A (0.41) ALOX5MAPTALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200227644-A1 ORGANIC LIGHT-EMITTING DIODE OPERABLE AT LOW VOLTAGE WITH HIGH EFFICIENCY AND LONG LIFETIME SFC CO., LTD. (KR) 2020-07-16 — — US disclosed
EP-3660934-A1 ORGANIC LIGHT EMITTING ELEMENT CAPABLE OF DRIVING AT LOW VOLTAGE AND HAVING HIGH EFFICIENCY AND LONG LIFE CHARACTERISTICS SFC Co., Ltd. (KR) 2020-06-03 — — EP disclosed
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