Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 8/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30662565 | 0.99 | MKNK1 (0.43) | MKNK1MKNK2JAK3TTBK1TTBK2 | |
| SCHEMBL22061498 | 0.75 | MKNK1 (0.46) | MKNK1MKNK2TTBK1TTBK2 | |
| SCHEMBL22061389 | 0.74 | MKNK1 (0.43) | MKNK1JAK3TTBK1TTBK2TNNI3K | |
| Hydrochloric Acid SCHEMBL30662604 | 0.74 | MKNK1 (0.46) | MKNK1MKNK2TTBK1TTBK2 | |
| SCHEMBL22061567 | 0.73 | PRKCA (0.36) | — | |
| SCHEMBL22061125 | 0.71 | MKNK1 (0.45) | MKNK1TTBK1TTBK2TNNI3K | |
| SCHEMBL22061435 | 0.71 | MKNK1 (0.51) | MKNK1MKNK2TTBK1TTBK2TNNI3K | |
| SCHEMBL22061569 | 0.69 | MKNK2 (0.43) | MKNK2 | |
| SCHEMBL22061054 | 0.69 | MKNK1 (0.58) | MKNK1 | |
| SCHEMBL22060774 | 0.69 | MKNK1 (0.65) | MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253397-B | MNK inhibitors | 上海迪诺医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111253397-A | MNK inhibitors | 上海迪诺医药科技有限公司 | 2020-06-09 | — | — | CN | disclosed |
| WO-2020108619-A1 | MNK INHIBITOR | 上海迪诺医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |