Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22061568 | 0.73 | MKNK1 (0.43) | — | |
| SCHEMBL22061569 | 0.71 | MKNK2 (0.43) | PRKCAPRKCQ | |
| Hydrochloric Acid SCHEMBL30662588 | 0.70 | MKNK2 (0.42) | PRKCAPRKCQ | |
| SCHEMBL29361608 | 0.66 | TDP2 (0.35) | — | |
| SCHEMBL14991726 | 0.66 | TDP2 (0.35) | — | |
| SCHEMBL22367385 | 0.65 | PARP1 (0.42) | HTR2AHTR2CHTR2B | |
| SCHEMBL23009999 | 0.64 | PARP1 (0.40) | — | |
| SCHEMBL30106504 | 0.64 | KDM5A (0.37) | — | |
| SCHEMBL22061371 | 0.63 | KDM4E (0.33) | — | |
| SCHEMBL1854333 | 0.63 | PIK3CD (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253397-A | MNK inhibitors | 上海迪诺医药科技有限公司 | 2020-06-09 | — | — | CN | disclosed |
| WO-2020108619-A1 | MNK INHIBITOR | 上海迪诺医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |