Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 6/20 | 0.39 |
| ▸ | PRKCA | P17252 | 3/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30662588 | 0.99 | MKNK2 (0.42) | MKNK2METTL3PRKCAPRKCQPRMT5 | |
| SCHEMBL22061567 | 0.71 | PRKCA (0.36) | PRKCAPRKCQ | |
| SCHEMBL22061568 | 0.69 | MKNK1 (0.43) | MKNK2 | |
| SCHEMBL18165609 | 0.65 | MKNK2 (0.41) | MKNK2METTL3PRMT5 | |
| SCHEMBL18804771 | 0.64 | MKNK2 (0.47) | MKNK2METTL3PRMT5WDR77 | |
| SCHEMBL27306222 | 0.64 | PRKCA (0.33) | PRKCAPRKCQ | |
| SCHEMBL18811977 | 0.61 | MKNK2 (0.52) | MKNK2METTL3 | |
| SCHEMBL18789135 | 0.60 | MKNK2 (1.00) | MKNK2 | |
| SCHEMBL18789211 | 0.59 | MKNK2 (0.47) | MKNK2METTL3PRMT5WDR77 | |
| SCHEMBL18789153 | 0.59 | MKNK2 (0.67) | MKNK2METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111253397-B | MNK inhibitors | 上海迪诺医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111253397-A | MNK inhibitors | 上海迪诺医药科技有限公司 | 2020-06-09 | — | — | CN | disclosed |
| WO-2020108619-A1 | MNK INHIBITOR | 上海迪诺医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |