SCHEMBL22062049

SCHEMBL22062049

Cc1ccc(/N=N/Nc2cccc(Oc3ccccc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.49
CYP1A1 P04798 1/20 0.49
TSHR P16473 1/20 0.49
CYP1B1 Q16678 1/20 0.49
RAB9A P51151 9/20 0.46
NPC1 O15118 7/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
CASP3 P42574 2/20 0.46
SENP8 Q96LD8 2/20 0.46
SENP7 Q9BQF6 2/20 0.46
SENP6 Q9GZR1 2/20 0.46
MAPT P10636 9/20 0.46
SMN1; SMN2 Q16637 7/20 0.46
ALDH1A1 P00352 6/20 0.46
HPGD P15428 3/20 0.46
LMNA P02545 3/20 0.42
MAPK1 P28482 2/20 0.41
HTT P42858 3/20 0.40
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22062168 0.90 TDP1 (0.42) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL4751885 0.76 NPC1 (0.49) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL22062047 0.72 CYP1B1 (0.55) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL22062054 0.72 SIGMAR1 (0.53) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL15085780 0.72 SMN1; SMN2 (0.60) TDP1TSHRRAB9ANPC1MEN1
SCHEMBL9655209 0.72 RAB9A (0.67) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL2003780 0.72 RAB9A (0.67) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL22062152 0.72 RAB9A (0.67) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL431706 0.70 TDP1 (0.66) TDP1CYP1A1TSHRCYP1B1RAB9A
SCHEMBL27928538 0.70 NPC1 (0.47) TDP1CYP1A1TSHRCYP1B1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10678156-B2 Pigment dispersion, method for manufacturing toner, aqueous ink, and triazo compound CANON KABUSHIKI KAISHA (JP) 2020-06-09 US disclosed