Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865181 | 0.78 | GAA (0.48) | GAAMCOLN3PSIP1L3MBTL1ACHE | |
| SCHEMBL23720024 | 0.76 | GAA (0.47) | GAAMCOLN3PSIP1L3MBTL1ACHE | |
| SCHEMBL23720015 | 0.75 | GAA (0.45) | GAAMCOLN3PSIP1L3MBTL1ACHE | |
| SCHEMBL22026800 | 0.72 | GAA (0.52) | GAAMCOLN3PSIP1L3MBTL1ALDH1A1 | |
| SCHEMBL23720030 | 0.72 | GAA (0.42) | GAAMCOLN3PSIP1L3MBTL1ACHE | |
| SCHEMBL23720028 | 0.72 | GAA (0.42) | GAAMCOLN3PSIP1L3MBTL1ACHE | |
| SCHEMBL24483710 | 0.72 | GAA (0.43) | GAAMCOLN3PSIP1L3MBTL1ACHE | |
| SCHEMBL16865191 | 0.68 | MAPT (0.41) | GAAMCOLN3L3MBTL1ALDH1A1MAPT | |
| SCHEMBL28916526 | 0.68 | GAA (0.57) | GAAMCOLN3PSIP1HTR7ALDH1A1 | |
| SCHEMBL15237080 | 0.68 | GAA (0.47) | GAAMCOLN3PSIP1L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181192-A1 | DISULFIDE BIOCONJUGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181192-A1 | DISULFIDE BIOCONJUGATION | P4HB, PDIA6, PDIA5 | GAA 3650/4885MCOLN3 4307/4885PSIP1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.