SCHEMBL22064141 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	METAP2	P50579	8/20	0.35

▸	METAP1	P53582	6/20	0.35

▸	TSHR	P16473	3/20	0.35

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.33

▸	CA12	O43570	1/20	0.32

▸	CA7	P43166	1/20	0.32

▸	CA9	Q16790	1/20	0.32

▸	CA14	Q9ULX7	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29732165	0.82	CA14 (0.42)	TSHRSMN1; SMN2ALDH1A1CA12CA14
SCHEMBL18924153	0.77	DPP4 (0.46)	METAP2METAP1TSHRSMN1; SMN2ALDH1A1
SCHEMBL807266	0.77	TSHR (0.45)	TSHRSMN1; SMN2ALDH1A1CA14
SCHEMBL18726371	0.77	TSHR (0.45)	TSHRSMN1; SMN2ALDH1A1CA14
SCHEMBL21952842	0.77	METAP2 (0.44)	METAP2METAP1TSHRSMN1; SMN2ALDH1A1
SCHEMBL18924152	0.75	TSHR (0.36)	TSHRALDH1A1
SCHEMBL18556386	0.74	TSHR (0.39)	METAP2METAP1TSHRSMN1; SMN2ALDH1A1
SCHEMBL27448207	0.74	CYP2D6 (0.41)	—
SCHEMBL24469367	0.74	ALDH1A1 (0.31)	SMN1; SMN2ALDH1A1
SCHEMBL21699485	0.74	ALDH1A1 (0.31)	SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3189056-B1	CYTOTOXIC BENZODIAZEPINE DERIVATIVES	IMMUNOGEN INC (US)	2020-06-10	—	—	EP	disclosed