SCHEMBL22064243

SCHEMBL22064243

CC(Cc1ccccc1)C(=O)OCc1ccc(I)cc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
CTSB P07858 2/20 0.46
LTA4H P09960 1/20 0.46
LAP3 P28838 1/20 0.46
HPGD P15428 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
APP P05067 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SIGMAR1 Q99720 2/20 0.43
CTRB1 P17538 2/20 0.43
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38661393 1.00 ALDH1A1 (0.49) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL265176 0.91 ALDH1A1 (0.58) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL12764099 0.91 ALDH1A1 (0.58) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL265561 0.91 ALDH1A1 (0.58) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL8268036 0.88 LMNA (0.54) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL16080197 0.88 LMNA (0.54) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL13534745 0.86 ALDH1A1 (0.50) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL14599839 0.86 ALDH1A1 (0.50) ALDH1A1CTSBLTA4HLAP3HPGD
SCHEMBL25901508 0.84 LTA4H (0.65) LTA4HLAP3L3MBTL1PPARGPPARA
SCHEMBL8268038 0.82 PPARG (0.50) LTA4HLAP3L3MBTL1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200183280-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2020-06-11 US disclosed