Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | PNP | P00491 | 3/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10910754 | 0.93 | MAPT (0.58) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| Leucopterin SCHEMBL14080077 | 0.81 | MAPT (0.73) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| SCHEMBL22144 | 0.79 | MAPT (1.00) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| SCHEMBL159446 | 0.78 | MAPT (0.68) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| SCHEMBL447389 | 0.75 | MAPT (0.84) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7296117 | 0.73 | MAPT (0.81) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| SCHEMBL5479007 | 0.73 | MAPT (0.62) | MAPTPNPDYRK1AKDM4EALDH1A1 | |
| 8-Aminoguanine SCHEMBL21761 | 0.67 | PNP (1.00) | MAPTPNPKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8133247 | 0.67 | PNP (0.59) | MAPTPNPKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3513712 | 0.67 | MAPT (0.75) | MAPTPNPDYRK1AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2015-06-11 | — | — | US | claimed |
| WO-2014003950-A2 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2014-01-03 | — | — | WO | claimed |
| US-7982030-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-07-19 | — | — | US | claimed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | claimed |
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | claimed |
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2015-06-11 | — | — | US | disclosed |
| WO-2014003950-A2 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | disclosed |
| US-4536571-A | SEFL-DETOXIFYING ANTICARCINOGENIC AGENT | STOCKEL RICHARD F (US) | 1985-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | MAPT 3069/4885PNP 5/4885DYRK1A 3755/4885 |
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SLC28A1, SLC28A2, SLC5A6 | MAPT 3794/4885PNP 8/4885DYRK1A 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.