Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 10/20 | 0.49 |
| ▸ | KDR | P35968 | 9/20 | 0.49 |
| ▸ | FLT1 | P17948 | 6/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | TEK | Q02763 | 2/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22024855 | 0.80 | KDR (0.53) | EPHB4KDRFLT1ABL1EGFR | |
| SCHEMBL22024568 | 0.79 | KDR (0.53) | EPHB4KDRFLT1ABL1EGFR | |
| SCHEMBL22066418 | 0.77 | CYP3A4 (0.43) | KDRFYNALDH1A1LMNAMEN1 | |
| SCHEMBL22066326 | 0.73 | KDR (0.44) | EPHB4KDRTEKALDH1A1L3MBTL1 | |
| SCHEMBL11642147 | 0.72 | MAPT (0.79) | KDRFLT1ABL1EGFRPDGFRB | |
| SCHEMBL22024854 | 0.71 | EPHB4 (0.60) | EPHB4KDRFLT1ABL1EGFR | |
| SCHEMBL22024648 | 0.71 | EPHB4 (0.52) | EPHB4KDRFLT1ABL1EGFR | |
| SCHEMBL22025032 | 0.71 | EPHB4 (0.57) | EPHB4KDRFLT1ABL1EGFR | |
| SCHEMBL22024565 | 0.71 | KDR (0.53) | EPHB4KDRFLT1ABL1EGFR | |
| SCHEMBL22025542 | 0.71 | EPHB4 (0.59) | EPHB4KDRFLT1ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663293-A1 | SUBSTITUTED PENTA- AND HEXA-HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, DRUG COMBINATION AND USE THEREOF | Xiamen University (CN) | 2020-06-10 | — | — | EP | disclosed |