Sugi Predict

Sugi Predict / Compounds / SCHEMBL220681

SCHEMBL220681

SCHEMBL220681

COc1ccc(C(=O)Cl)c(OC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 3/20 0.64
▸ MAPT P10636 4/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ RAD52 P43351 1/20 0.58
▸ ABCG2 Q9UNQ0 4/20 0.57
▸ KMT2A Q03164 4/20 0.55
▸ TNFRSF1A P19438 1/20 0.55
▸ GAA P10253 1/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ LMNA P02545 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ PDE4A P27815 1/20 0.54
▸ PDE4B Q07343 1/20 0.54
▸ PDE4C Q08493 1/20 0.54
▸ PDE4D Q08499 1/20 0.54
▸ TP53 P04637 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ CYP1A2 P05177 1/20 0.54
▸ CYP3A4 P08684 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL28828135 0.92 NPC1 (0.55) NPC1MAPTALDH1A1HPGDRAD52
SCHEMBL8675965 0.90 NPC1 (0.54) NPC1MAPTALDH1A1HPGDRAD52
Toluene SCHEMBL27923258 0.89 NPC1 (0.55) NPC1MAPTALDH1A1HPGDRAD52
SCHEMBL27580216 0.86 KDM4E (0.58) NPC1MAPTALDH1A1HPGDRAD52
SCHEMBL805920 0.86 KDM4E (0.58) NPC1MAPTALDH1A1HPGDKMT2A
SCHEMBL11252289 0.86 KDM4E (0.55) NPC1MAPTHPGDLMNASMN1; SMN2
SCHEMBL24001 0.85 MAPT (0.66) NPC1MAPTALDH1A1HPGDABCG2
SCHEMBL7017038 0.84 KDM4E (0.58) NPC1MAPTALDH1A1KMT2AMEN1
SCHEMBL20204164 0.84 TP53 (0.48) NPC1MAPTALDH1A1HPGDRAD52
SCHEMBL285924 0.84 NPC1 (0.79) NPC1MAPTALDH1A1HPGDRAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118599293-A Key cap wear-resistant material for man-machine interaction equipment and preparation method thereof 江苏传艺科技股份有限公司 2024-09-06 — — CN claimed
CN-116253638-A Method for synthesizing 2, 4-dimethoxy benzoyl chloride and 2, 4-dimethoxy benzoic acid 重庆长风化学工业有限公司 2023-06-13 — — CN claimed
CN-105985306-A Total synthesis preparation method of natural product flavonoid compounds 复旦大学 2016-10-05 — — CN claimed
CN-103709130-B Synthetic methods and applications of natural products with pancrelipase inhibition activity UNIV FUDAN 2015-05-13 — — CN claimed
CN-103342690-B Preparation method of morin NANJING UNIVERSITY OF TECHNOLOGY 2015-04-22 — — CN claimed
CN-104016957-A 7-methyl-3-geranyl flavone and 7-methyl-3-isopentene group flavone as well as preparation method and application thereof UNIV GUANGXI TEACHERS EDUCATION 2014-09-03 — — CN claimed
CN-104003967-A 5,7,2,, 4,-tetramethoxy-3-alkyl flavone, its preparation method and application UNIV GUANGXI TEACHERS EDUCATION 2014-08-27 — — CN claimed
CN-104003970-A Natural product Albanin A/E analogue, preparation method of natural product Albanin A/E analogue, and application of natural product Albanin A/E analogue UNIV GUANGXI TEACHERS EDUCATION 2014-08-27 — — CN claimed
CN-103709130-A Synthetic methods and applications of natural products with pancrelipase inhibition activity UNIV FUDAN 2014-04-09 — — CN claimed
CN-103342690-A Preparation method of morin NANJING UNIVERSITY OF TECHNOLOGY 2013-10-09 — — CN claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 — — EP claimed
US-5268423-A Solid phase phenyl ether resin in presence of a Lewis acid acid catalyst NEW YORK UNIVERSITY (US) 1993-12-07 — — US claimed
WO-1993017056-A1 METHOD FOR PREPARATION OF PEPTIDE SYNTHESIS RESINS AND NOVEL PEPTIDE SYNTHESIS RESINS NEW YORK UNIVERSITY (US) 1993-09-02 — — WO claimed
US-20260139000-A1 METHOD FOR PRODUCING 2' MODIFIED PYRIMIDINE NUCLEOSIDE NISSAN CHEMICAL CORPORATION (JP) 2026-05-21 — — US disclosed
US-12624288-B2 Mixture including ferroelectric nematic phase and methods of forming and using same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2026-05-12 — — US disclosed
EP-3713925-B1 SYNTHESIS OF MORIN AND MORIN DERIVATIVES ORSATEC GMBH (DE) 2026-04-22 — — EP disclosed
US-4026891-A HYPOTENSIVE AGENTS, ANTITHROMBOTICS, AND CARDIOTONICS BOEHRINGER INGELHEIM GMBH (DT) 1977-05-31 — — US disclosed
US-4024153-A ULTRAVIOLET STABILIZERS EASTMAN KODAK COMPANY (US) 1977-05-17 — — US disclosed
US-4010279-A BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE BOEHRINGER INGELHEIM GMBH (DT) 1977-03-01 — — US disclosed
US-3954706-A Polychromophoric benzotriazole ultraviolet stabilizers for organic compositions EASTMAN KODAK COMPANY (US) 1976-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624288-B2 Mixture including ferroelectric nematic phase and methods of forming and using same NOTCH2, NUCB2, NOTCH4 NPC1 754/4885MAPT 1522/4885ALDH1A1 4582/4885
US-20260139000-A1 METHOD FOR PRODUCING 2' MODIFIED PYRIMIDINE NUCLEOSIDE ALKBH1, DUT, NSUN2 NPC1 3165/4885MAPT 4773/4885ALDH1A1 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.