SCHEMBL285924

SCHEMBL285924

COc1ccc(C(=O)c2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.79
LMNA P02545 3/20 0.66
KMT2A Q03164 2/20 0.66
CYP1A2 P05177 2/20 0.66
CYP3A4 P08684 2/20 0.66
CYP2C19 P33261 2/20 0.66
MEN1 O00255 1/20 0.66
TSHR P16473 1/20 0.66
RAB9A P51151 2/20 0.66
MAPT P10636 5/20 0.61
ALDH1A1 P00352 2/20 0.61
HPGD P15428 2/20 0.61
RAD52 P43351 1/20 0.61
ABCG2 Q9UNQ0 2/20 0.60
HTT P42858 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
TNFRSF1A P19438 1/20 0.58
GAA P10253 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
PDE4A P27815 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31575666 1.00 NPC1 (0.79) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL6663420 0.91 NPC1 (0.83) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL3236831 0.91 NPC1 (0.68) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL7331211 0.89 NPC1 (0.66) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL6373100 0.89 NPC1 (0.66) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL4841826 0.89 NPC1 (0.66) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL29414999 0.89 NPC1 (1.00) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL5902231 0.89 NPC1 (1.00) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL15125786 0.87 NPC1 (0.62) NPC1LMNAKMT2ACYP1A2CYP3A4
SCHEMBL5709863 0.87 NPC1 (0.75) NPC1LMNAKMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952497-A USEFUL IN PEPTIDE, POLYPEPTIDE AND PROTEIN SYNTHESIS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 1999-09-14 US claimed
EP-0166151-B1 NOVEL EXTRACTANTS AND METHOD FOR THE RECOVERY OF PALLADIUM AlliedSignal Inc. (US) 1989-05-03 EP claimed
JP-60016948-A None JP disclosed
US-12534548-B2 Bleaching agent, preparation and use of the same with polymerizable compositions for optical materials MITSUI CHEMICALS, INC. (JP) 2026-01-27 US disclosed
US-12448470-B2 Polymerizable composition for optical material, molded product, optical material, and plastic lens and method for manufacturing same MITSUI CHEMICALS, INC. (JP) 2025-10-21 US disclosed
US-12189290-B2 Photosensitive resin composition, dry film using same, printed wiring board, and printed wiring board manufacturing method RESONAC CORPORATION (JP) 2025-01-07 US disclosed
US-20250002724-A1 METHOD FOR MANUFACTURING AN OPTICAL MATERIAL AND COMPOSITION USED IN THIS METHOD MITSUI CHEMICALS, INC. (JP) 2025-01-02 US disclosed
EP-3722840-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND MOLDED ARTICLE MITSUI CHEMICALS INC (JP) 2024-12-04 EP disclosed
US-11921424-B2 Photosensitive resin composition, dry film using same, printed wiring board, and printed wiring board manufacturing method Hitachi Chemical Company, Ltd. (FIPAS) (JP) 2024-03-05 US disclosed
EP-4327139-A1 METHOD FOR MANUFACTURING AN OPTICAL MATERIAL AND COMPOSITION USED IN THIS METHOD Mitsui Chemicals, Inc. (JP) 2024-02-28 EP disclosed
US-11822242-B2 DNQ-type photoresist composition including alkali-soluble acrylic resins MERCK PATENT GMBH (DE) 2023-11-21 US disclosed
US-20100286359-A1 Solid Support for FMOC-Solid Phase Synthesis of Peptide Acids MALLINCKRODT INC. (US) 2010-11-11 US disclosed
EP-1038870-A1 3,3-bis(aryl)-5-((N-(un)substituted)amido)naphthopyrans, their preparation, compositions and (co)polymer matrices containing them Corning S.A. (FR) 2000-09-27 EP disclosed
US-5728888-A Preparation of hydroxylated benzophenones BASF AKTIENGESELLSCHAFT (DE) 1998-03-17 US disclosed
EP-0792861-A1 Process for preparing hydroxylated benzophenones BASF AKTIENGESELLSCHAFT (DE) 1997-09-03 EP disclosed
US-5110940-A Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase BRISTOL-MYERS COMPANY (US) 1992-05-05 US disclosed
US-5068346-A Anticholesterol agents BRISTOL-MYERS COMPANY (US) 1991-11-26 US disclosed
US-4897490-A DERIVATIVES OF BETA-HYDROXY,OMEGA-DIPHENYL,TETRAZOL-5-YL ALK-OMEGA-ENOIC ACID, ESTER OR LACTONE BRISTOL-MEYERS COMPANY (US) 1990-01-30 US disclosed
WO-1988006584-A1 ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS BRISTOL-MYERS COMPANY (US) 1988-09-07 WO disclosed
JP-S6016948-A PRODUCTION OF METHOXYBENZOPHENONE COMPOUND ISHIHARA SANGYO KAISHA LTD 1985-01-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286359-A1 Solid Support for FMOC-Solid Phase Synthesis of Peptide Acids MAX, NPPA, PTMS NPC1 2052/4885LMNA 3522/4885KMT2A 1489/4885
US-12534548-B2 Bleaching agent, preparation and use of the same with polymerizable compositions for optical materials HBB, HBZ, CASP12 NPC1 1874/4885LMNA 1460/4885KMT2A 2307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.