⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069334 | 0.89 | L3MBTL1 (0.34) | — | |
| SCHEMBL22069257 | 0.81 | BRD4 (0.31) | — | |
| SCHEMBL22069438 | 0.80 | — | — | |
| SCHEMBL22069337 | 0.70 | PDE10A (0.34) | — | |
| SCHEMBL22718587 | 0.69 | MAPT (0.36) | — | |
| SCHEMBL22719403 | 0.68 | MTHFD2 (0.33) | — | |
| SCHEMBL22069029 | 0.67 | MAPT (0.34) | — | |
| SCHEMBL22069259 | 0.64 | — | — | |
| SCHEMBL21855451 | 0.61 | DPP4 (0.35) | — | |
| SCHEMBL22716158 | 0.61 | MTHFD2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210252014-A1 | OXADIAZEPINONE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | NOVIRA THERAPEUTICS INC (US) | 2021-08-19 | — | — | US | disclosed |
| EP-3478692-B1 | OXADIAZEPINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEPATITIS B INFECTIONS | NOVIRA THERAPEUTICS INC (US) | 2020-06-17 | — | — | EP | disclosed |