Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.63 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859313 | 0.87 | HSPB1 (0.82) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL22966266 | 0.84 | PDE7A (0.55) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL22069593 | 0.84 | PDE7A (0.74) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL22069708 | 0.84 | HSPB1 (0.68) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL5167786 | 0.84 | ALDH1A1 (0.71) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL31287841 | 0.84 | HSPB1 (0.82) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3143655 | 0.83 | KMT2A (0.69) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL3131710 | 0.81 | HSPB1 (0.68) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL29351876 | 0.81 | HSPB1 (0.68) | HSPB1PDE7AMEN1KMT2AALDH1A1 | |
| SCHEMBL22069702 | 0.81 | HSPB1 (0.68) | HSPB1PDE7AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |