Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061605 | 0.86 | GAA (0.45) | ALDH1A1SIGMAR1KMT2AAMPD2 | |
| SCHEMBL3144024 | 0.77 | AMPD2 (0.40) | DRD2DRD4KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL22069780 | 0.71 | SLC6A3 (0.41) | DRD2ALDH1A1SIGMAR1KMT2A | |
| SCHEMBL941871 | 0.71 | KDM4E (0.62) | KDM4EALDH1A1SIGMAR1KMT2ACCR5 | |
| SCHEMBL21244555 | 0.69 | GAA (0.47) | KDM4EALDH1A1SIGMAR1KMT2AAMPD2 | |
| SCHEMBL22069818 | 0.68 | — | — | |
| SCHEMBL4036910 | 0.68 | DDB1 (0.45) | DRD2SIGMAR1KMT2A | |
| SCHEMBL21748908 | 0.67 | DDB1 (0.44) | DRD2SIGMAR1KMT2A | |
| SCHEMBL22069785 | 0.66 | MEN1 (0.30) | KMT2A | |
| SCHEMBL3140906 | 0.66 | KDM4E (0.46) | DRD2DRD4KDM4EALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666757-A1 | PROCESS FOR PREPARING A PIPERIDIN-4-ONE | Karl-Franzens-Universität Graz (AT) | 2020-06-17 | — | — | EP | disclosed |