Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061605 | 0.84 | GAA (0.45) | GAAL3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL22069808 | 0.75 | HTR2A (0.55) | GAAL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL22069818 | 0.74 | — | — | |
| SCHEMBL27727732 | 0.73 | SLC6A3 (0.53) | SLC6A3SIGMAR1ACHE | |
| SCHEMBL486687 | 0.72 | SLC6A3 (0.66) | SLC6A3L3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL8108965 | 0.72 | SLC6A3 (0.66) | SLC6A3L3MBTL1MEN1KMT2ASIGMAR1 | |
| SCHEMBL11029384 | 0.72 | SIGMAR1 (0.46) | SLC6A3BDKRB2GAAL3MBTL1MEN1 | |
| SCHEMBL21244555 | 0.71 | GAA (0.47) | GAAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL11018891 | 0.71 | SIGMAR1 (0.47) | SLC6A3L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL22069772 | 0.71 | HSD11B1 (0.42) | KMT2ASIGMAR1ALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666757-A1 | PROCESS FOR PREPARING A PIPERIDIN-4-ONE | Karl-Franzens-Universität Graz (AT) | 2020-06-17 | — | — | EP | disclosed |