Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367212 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL12023267 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL15800482 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL30366945 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL437168 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL2496114 | 0.79 | SIGMAR1 (0.38) | PNMTSIGMAR1CYP3A4 | |
| SCHEMBL14335852 | 0.77 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL13071176 | 0.77 | PNMT (0.38) | PNMTGID4CYP3A4TSHRPIK3CA | |
| SCHEMBL14701851 | 0.77 | PNMT (0.38) | PNMTGID4CYP3A4TSHRPIK3CA | |
| SCHEMBL10140287 | 0.76 | PNMT (0.33) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924989-A | Synthesis method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid | 山东润博生物科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-3677572-B1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | JAPAN FINECHEM COMPANY INC (JP) | 2023-06-07 | — | — | EP | disclosed |
| EP-3677572-A1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | Japan Finechem Company, Inc. (JP) | 2020-07-08 | — | — | EP | disclosed |
| US-20200181091-A1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | JAPAN FINECHEM COMPANY, INC. (JP) | 2020-06-11 | — | — | US | disclosed |
| CN-110891940-A | Process for preparing pyrazole-4-carboxamide derivatives | 日本凡凯姆股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| EP-3604282-A1 | METHOD FOR PRODUCING HALOGEN-CONTAINING PYRAZOL CARBOXYLIC ACID AND INTERMEDIATE THEREOF | AGC Inc. (JP) | 2020-02-05 | — | — | EP | disclosed |
| EP-3604283-A1 | PRODUCTION METHOD FOR HALOGENATED PYRAZOLECARBOXYLIC ACID | AGC Inc. (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-20190225585-A1 | METHOD OF PRODUCING FLUORINE-CONTAINING PYRAZOLE CARBOXYLIC ACID HALIDE | AGC Inc. (JP) | 2019-07-25 | — | — | US | disclosed |
| EP-3492453-A1 | METHOD OF PRODUCING FLUORINE-CONTAINING PYRAZOLE CARBOXYLIC ACID HALIDE | AGC INC. (JP) | 2019-06-05 | — | — | EP | disclosed |
| EP-2632901-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE-4-CARBOXAMIDES | SOLVAY (BE) | 2018-09-12 | — | — | EP | disclosed |
| US-7781615-B2 | Process for the preparation of amines | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781615-B2 | Process for the preparation of amines | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| WO-2009138375-A1 | PROCESS FOR THE PREPARATION OF AMIDES | SYNGENTA LIMITED (GB) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009135860-A1 | METHOD FOR MANUFACTURING ARYL CARBOXAMIDES | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-2076123-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED BROMOBENZENES | Syngenta Limited (GB) | 2009-07-08 | — | — | EP | disclosed |
| EP-2066617-A1 | PROCESS FOR THE PRODUCTION OF AROMATIC AMINES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND | Syngeta Participations AG (CH) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008049507-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED BROMOBENZENES | SYNGENTA LIMITED (GB) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008017443-A1 | PROCESS FOR THE PRODUCTION OF AROMATIC AMINES IN THE PRESENCE OF A PALLADIUM COMPLEX COMPRISING A FERROCENYL BIPHOSPHINE LIGAND | SYNGENTA PARTICIPATIONS AG (CH) | 2008-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225585-A1 | METHOD OF PRODUCING FLUORINE-CONTAINING PYRAZOLE CARBOXYLIC ACID HALIDE | AFF1, CYP2F1, AFF2 | PNMT 4255/4885SIGMAR1 65/4885GID4 4577/4885 |
| US-20200181091-A1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | AADAC, CYP3A4, ABAT | PNMT 147/4885SIGMAR1 2557/4885GID4 1508/4885 |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | HRH3, PAH, C1R | PNMT 200/4885SIGMAR1 899/4885GID4 3574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.