Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367212 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL12023267 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL220702 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL15800482 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL30366945 | 1.00 | PNMT (0.35) | PNMTSIGMAR1GID4CYP3A4TSHR | |
| SCHEMBL2496114 | 0.79 | SIGMAR1 (0.38) | PNMTSIGMAR1CYP3A4 | |
| SCHEMBL14335852 | 0.77 | SIGMAR1 (0.42) | SIGMAR1 | |
| SCHEMBL13071176 | 0.77 | PNMT (0.38) | PNMTGID4CYP3A4TSHRPIK3CA | |
| SCHEMBL14701851 | 0.77 | PNMT (0.38) | PNMTGID4CYP3A4TSHRPIK3CA | |
| SCHEMBL10140287 | 0.76 | PNMT (0.33) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924989-A | Synthesis method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxylic acid | 山东润博生物科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-3677572-B1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | JAPAN FINECHEM COMPANY INC (JP) | 2023-06-07 | — | — | EP | disclosed |
| EP-3677572-A1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | Japan Finechem Company, Inc. (JP) | 2020-07-08 | — | — | EP | disclosed |
| US-20200181091-A1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | JAPAN FINECHEM COMPANY, INC. (JP) | 2020-06-11 | — | — | US | disclosed |
| CN-110891940-A | Process for preparing pyrazole-4-carboxamide derivatives | 日本凡凯姆股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| EP-2640707-B1 | 5-HALOGENOPYRAZOLECARBOXAMIDES | BAYER IP GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |
| US-8680337-B2 | Process for the production of amides | Sungenta Limited (GB) | 2014-03-25 | — | — | US | disclosed |
| EP-2253623-B1 | New crystal form of a pyrazole fungicide | SYNGENTA PARTICIPATIONS AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130253225-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | SYNGENTA LIMITED (GB) | 2013-09-26 | — | — | US | disclosed |
| EP-2081884-B1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| US-20090306166-A1 | Method of Controlling Phytopathogenic Diseases on Turfgrass | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090306166-A1 | Method of Controlling Phytopathogenic Diseases on Turfgrass | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| US-20090221588-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221588-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090163569-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090163569-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| WO-2008037460-A1 | PROCESS FOR THE PREPARATION OF AMINES. | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-03 | — | — | WO | disclosed |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, INC. (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | SYNGENTA CROP PROTECTION, INC. (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181091-A1 | PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE | AADAC, CYP3A4, ABAT | PNMT 147/4885SIGMAR1 2557/4885GID4 1508/4885 |
| US-20090221588-A1 | FUNGICIDAL COMPOSITIONS | TUBB2B, TUBB, TUBB4B | PNMT 1480/4885SIGMAR1 2549/4885GID4 4159/4885 |
| US-20070265267-A1 | FUNGICIDAL COMPOSITIONS | CRY1, ERG28, DDT | PNMT 223/4885SIGMAR1 2774/4885GID4 1868/4885 |
| US-20070244121-A1 | Synergistic Fungicidal Compositions | DDT, CRY1, HCN1 | PNMT 176/4885SIGMAR1 1578/4885GID4 1914/4885 |
| US-20130253225-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | CFH, C5, CFB | PNMT 3296/4885SIGMAR1 673/4885GID4 2894/4885 |
| US-20090163569-A1 | PROCESS FOR THE PRODUCTION OF AMIDES | C5, CFH, C9 | PNMT 2975/4885SIGMAR1 679/4885GID4 3222/4885 |
| US-20090306166-A1 | Method of Controlling Phytopathogenic Diseases on Turfgrass | MAPT, TBCA, TTL | PNMT 407/4885SIGMAR1 4815/4885GID4 1632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.