Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072994 | 0.95 | KDM4E (0.35) | KDM4ETDP1SLC18A3L3MBTL3L3MBTL1 | |
| SCHEMBL22073010 | 0.93 | KDM4E (0.37) | KDM4ETDP1SLC18A3 | |
| SCHEMBL15323355 | 0.90 | — | — | |
| SCHEMBL8901941 | 0.88 | — | — | |
| SCHEMBL30909113 | 0.82 | L3MBTL3 (0.36) | KDM4ETDP1SLC18A3L3MBTL3L3MBTL1 | |
| SCHEMBL2974735 | 0.80 | KMT2A (0.33) | TDP1L3MBTL3L3MBTL1 | |
| SCHEMBL29270116 | 0.78 | HTR6 (0.47) | — | |
| SCHEMBL736888 | 0.78 | — | — | |
| SCHEMBL20777904 | 0.76 | L3MBTL3 (0.39) | KDM4ETDP1SLC18A3L3MBTL3L3MBTL1 | |
| SCHEMBL2968855 | 0.74 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117942-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-11 | — | — | WO | disclosed |