Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PTGIR | P43119 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429828 | 0.88 | SIGMAR1 (0.62) | MAOAMAOBSIGMAR1SMN1; SMN2PTGIR | |
| SCHEMBL22468374 | 0.85 | SIGMAR1 (0.60) | MAOAMAOBSIGMAR1SMN1; SMN2PTGIR | |
| SCHEMBL10729859 | 0.81 | ALDH1A1 (0.55) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL979576 | 0.81 | SIGMAR1 (0.69) | MAOAMAOBSIGMAR1SMN1; SMN2PTGIR | |
| SCHEMBL19285228 | 0.80 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2PTGIRCHKAALDH1A1 | |
| SCHEMBL20804352 | 0.80 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2PTGIRCHKAALDH1A1 | |
| SCHEMBL1043952 | 0.80 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2PTGIRCHKAALDH1A1 | |
| Hydrochloric Acid SCHEMBL10734488 | 0.79 | ALDH1A1 (0.53) | MAOAMAOBSIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10734307 | 0.79 | MAOA (0.48) | MAOAMAOBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL10733638 | 0.77 | MAOA (0.47) | MAOAMAOBDRD2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890936-A | Synthetic method of 5, 6-dihydro-2 (1H) -pyridone | 南京师范大学 | 2022-08-12 | — | — | CN | claimed |
| CN-114890936-B | Synthesis method of 5, 6-dihydro-2 (1H) -pyridone | 南京师范大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-114890936-B | Synthesis method of 5, 6-dihydro-2 (1H) -pyridone | 南京师范大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-116694374-A | System for synthesizing 5, 6-dihydro-2 (IH) -pyridone based on photo-thermal and zero pollution extraction | 常州大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114890936-A | Synthetic method of 5, 6-dihydro-2 (1H) -pyridone | 南京师范大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114890936-A | Synthetic method of 5, 6-dihydro-2 (1H) -pyridone | 南京师范大学 | 2022-08-12 | — | — | CN | disclosed |
| WO-2020117942-A1 | CHOLINE METABOLISM INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-11 | — | — | WO | disclosed |