Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28609534 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL22078120 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL22077691 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL22033612 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL22078395 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL19526512 | 0.95 | MEN1 (0.56) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL22033505 | 0.95 | ALDH1A1 (0.56) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL293781 | 0.95 | MEN1 (0.56) | ALDH1A1MEN1HPGDKMT2AFFAR4 | |
| SCHEMBL22033629 | 0.94 | ALDH1A1 (0.55) | ALDH1A1MEN1HPGDKMT2ACETP | |
| SCHEMBL20966571 | 0.88 | GPR84 (0.51) | ALDH1A1MEN1HPGDKMT2ACETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074866-A1 | MODIFIED AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. | 2025-03-06 | — | — | US | disclosed |
| US-12077483-B2 | Modified amine lipids | INTELLIA THERAPEUTICS, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| US-20220119341-A1 | MODIFIED AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
| US-20220119341-A1 | MODIFIED AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. | 2022-04-21 | — | — | US | disclosed |
| CN-113260607-A | Modified amine lipids | 英特利亚治疗股份有限公司 | 2021-08-13 | — | — | CN | disclosed |
| WO-2020118041-A1 | MODIFIED AMINE LIPIDS | INTELLIA THERAPEUTICS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12077483-B2 | Modified amine lipids | PHOSPHO1, SGMS1, SGMS2 | ALDH1A1 1817/4885MEN1 762/4885HPGD 2878/4885 |
| US-20220119341-A1 | MODIFIED AMINE LIPIDS | PHOSPHO1, SGMS1, SGMS2 | ALDH1A1 1817/4885MEN1 762/4885HPGD 2878/4885 |
| US-20250074866-A1 | MODIFIED AMINE LIPIDS | PHOSPHO1, SGMS1, SGMS2 | ALDH1A1 1817/4885MEN1 762/4885HPGD 2878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.