Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080295 | 0.85 | NPC1 (0.55) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22079664 | 0.84 | RAB9A (0.54) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22079647 | 0.83 | NPC1 (0.53) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22079984 | 0.81 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22079662 | 0.76 | KDM4E (0.53) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL471629 | 0.73 | HPGD (0.61) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22079991 | 0.73 | HPGD (0.53) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL22080098 | 0.72 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22079660 | 0.71 | NPC1 (0.50) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL22080009 | 0.71 | CYP4F2 (0.46) | KMT2AMEN1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114150-A1 | SYNTHESIS METHOD FOR SYNTHESIZING CARBAMATE USING DIMETHYL SULFOXIDE YLIDE, AMINE AND CARBON DIOXIDE | 华南理工大学 | 2020-06-11 | — | — | WO | disclosed |