Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22079647 | 0.87 | NPC1 (0.53) | NPC1RAB9AHPGDL3MBTL1KMT2A | |
| SCHEMBL22079635 | 0.86 | NPC1 (0.49) | NPC1RAB9AHPGDL3MBTL1KMT2A | |
| SCHEMBL3083608 | 0.77 | CCR6 (0.58) | HPGDL3MBTL1TP53KMT2ALMNA | |
| SCHEMBL6174141 | 0.77 | LMNA (0.51) | HPGDL3MBTL1TP53KMT2ALMNA | |
| SCHEMBL10606452 | 0.75 | KMT2A (0.55) | NPC1RAB9AHPGDL3MBTL1TP53 | |
| SCHEMBL7611620 | 0.75 | MAPT (0.62) | NPC1RAB9AHPGDL3MBTL1KMT2A | |
| SCHEMBL17064836 | 0.75 | ALDH1A1 (0.50) | NPC1RAB9AHPGDL3MBTL1TP53 | |
| SCHEMBL2175972 | 0.74 | NPC1 (0.57) | NPC1RAB9AHPGDL3MBTL1TP53 | |
| SCHEMBL31126882 | 0.74 | LMNA (0.53) | NPC1RAB9ATP53KMT2ALMNA | |
| SCHEMBL1907159 | 0.73 | NPC1 (0.61) | NPC1RAB9AHPGDL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114150-A1 | SYNTHESIS METHOD FOR SYNTHESIZING CARBAMATE USING DIMETHYL SULFOXIDE YLIDE, AMINE AND CARBON DIOXIDE | 华南理工大学 | 2020-06-11 | — | — | WO | disclosed |