Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | PKM | P14618 | 3/20 | 0.72 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.70 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | MERTK | Q12866 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24169332 | 0.85 | RAB9A (0.97) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL14758331 | 0.85 | SLC2A1 (0.68) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL4486503 | 0.85 | NPC1 (0.96) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL29357942 | 0.85 | NPC1 (0.96) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL2590796 | 0.84 | NPY5R (0.97) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL31087716 | 0.84 | RAB9A (1.00) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL25284090 | 0.84 | RAB9A (1.00) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL21500665 | 0.84 | NPC1 (0.77) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL8909187 | 0.83 | NPY5R (1.00) | NPC1RAB9AKMT2AMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL8897702 | 0.83 | NPY5R (0.94) | NPC1RAB9AKMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-01-27 | — | — | US | disclosed |
| WO-2020118036-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | CLPP, SPOUT1, MRPL21 | NPC1 1188/4885RAB9A 1651/4885KMT2A 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.