Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 10/20 | 0.36 |
| ▸ | CA1 | P00915 | 10/20 | 0.36 |
| ▸ | CA2 | P00918 | 10/20 | 0.36 |
| ▸ | CA9 | Q16790 | 10/20 | 0.36 |
| ▸ | CA7 | P43166 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24257959 | 0.83 | ALDH1A1 (0.49) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL24257973 | 0.82 | SOS1 (0.40) | SOS1CA12CA1CA2CA9 | |
| SCHEMBL31682072 | 0.80 | SOS1 (0.44) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL31681979 | 0.80 | SOS1 (0.44) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL31681975 | 0.80 | SOS1 (0.44) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL31682063 | 0.80 | SOS1 (0.44) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL31682067 | 0.80 | SOS1 (0.44) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL22106136 | 0.79 | SOS1 (0.42) | SOS1ALDH1A1HTTCA12CA1 | |
| SCHEMBL22079893 | 0.76 | CA12 (0.49) | CA12CA1CA2CA9CA7 | |
| SCHEMBL24257964 | 0.72 | CA12 (0.52) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
| US-20200181223-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181223-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | SOS1 911/4885ALDH1A1 1829/4885HTT 855/4885 |
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | SOS1 911/4885ALDH1A1 1829/4885HTT 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.