SCHEMBL24257973

SCHEMBL24257973

CC(C)(C)OCCC#Cc1ccc(Oc2cccc(S(N)(=O)=O)c2)cc1F

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 6/20 0.40
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
PTGES2 Q9H7Z7 1/20 0.36
HAO1 Q9UJM8 1/20 0.35
SLC6A4 P31645 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22080315 0.82 SOS1 (0.51) SOS1CA12CA1CA2CA9
SCHEMBL24257965 0.77 CA2 (0.52) CA12CA1CA2CA9PTGES2
SCHEMBL24257959 0.73 ALDH1A1 (0.49) SOS1CA12CA1CA2CA9
SCHEMBL24257958 0.69 CA2 (0.47) SOS1CA12CA1CA2CA9
SCHEMBL22079893 0.69 CA12 (0.49) CA12CA1CA2CA9
SCHEMBL24257964 0.65 CA12 (0.52) CA12CA1CA2CA9MEN1
SCHEMBL6014749 0.65 HTT (0.62) SOS1CA12CA1CA2CA9
SCHEMBL24257976 0.65 CA2 (0.54) CA12CA1CA2CA9
SCHEMBL6851534 0.64 SOS1 (0.69) SOS1CA12CA1CA2CA9
SCHEMBL31681975 0.64 SOS1 (0.44) SOS1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048968-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R SOS1 911/4885CA12 453/4885CA1 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.