Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 6/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16749648 | 0.93 | BCL2L1 (0.52) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL20882093 | 0.88 | BCL2L1 (0.42) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL5084654 | 0.87 | TSHR (0.57) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL18364480 | 0.84 | BCL2L1 (0.44) | BCL2L1BADTP53TSHRRXRA | |
| SCHEMBL5081784 | 0.81 | TSHR (0.52) | TP53TSHRCA12CA1CA2 | |
| SCHEMBL18364477 | 0.78 | TSHR (0.46) | TP53TSHRRXRARXRBCA12 | |
| SCHEMBL5082233 | 0.78 | RXRA (0.47) | TP53TSHRRXRARXRBSRD5A2 | |
| SCHEMBL16769658 | 0.78 | HSD17B10 (0.44) | BCL2L1BADRXRACA1CA2 | |
| SCHEMBL16769681 | 0.78 | HSD17B10 (0.44) | BCL2L1BADRXRACA1CA2 | |
| SCHEMBL11550092 | 0.76 | RXRA (0.46) | TP53TSHRRXRARXRBSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117833-A2 | AMORPHOUS METAL ORGANIC FRAMEWORKS AND METHODS OF PREPARING THE SAME | FRAMERGY INC. (US) | 2020-06-11 | — | — | WO | disclosed |