Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18364480 | 0.95 | BCL2L1 (0.44) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL5084654 | 0.90 | TSHR (0.57) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL16749648 | 0.84 | BCL2L1 (0.52) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL5081784 | 0.84 | TSHR (0.52) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL15132950 | 0.81 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL5082233 | 0.81 | RXRA (0.47) | TSHRTP53SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11550092 | 0.79 | RXRA (0.46) | TSHRTP53SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL22081978 | 0.78 | BCL2L1 (0.46) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL5084601 | 0.77 | TSHR (0.46) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL5470752 | 0.77 | TSHR (0.50) | TSHRTP53CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | HAO2, ASF1A, FTO | TSHR 4648/4885TP53 1115/4885SRD5A2 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.