SCHEMBL5082233

SCHEMBL5082233

CC12CC3(c4ccc(C(=O)O)cc4)CC(c4ccc(C(=O)O)cc4)(C1)CC(c1ccc(C(=O)O)cc1)(C2)C3

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXRA P19793 16/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
CYP26A1 O43174 3/20 0.44
CYP26B1 Q9NR63 2/20 0.44
RXRB P28702 9/20 0.44
RXRG P48443 7/20 0.44
RARB P10826 5/20 0.44
RARG P13631 5/20 0.44
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
RARA P10276 3/20 0.41
SRD5A2 P31213 1/20 0.41
CYP3A4 P08684 1/20 0.41
CRABP2 P29373 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11550092 0.98 RXRA (0.46) RXRATP53TSHRCYP26A1CYP26B1
SCHEMBL5084654 0.90 TSHR (0.57) RXRATP53TSHRALDH1A1SMN1; SMN2
SCHEMBL2747623 0.90 RXRA (0.43) RXRATP53TSHRCYP26A1CYP26B1
SCHEMBL5081784 0.84 TSHR (0.52) TP53TSHRALDH1A1SMN1; SMN2SRD5A2
SCHEMBL16749648 0.84 BCL2L1 (0.52) RXRATP53TSHRRXRBRXRG
SCHEMBL5568792 0.83 EPHX2 (0.42) RXRATP53TSHRCYP26A1CYP26B1
SCHEMBL18364477 0.81 TSHR (0.46) RXRATP53TSHRCYP26A1CYP26B1
SCHEMBL5480370 0.80 TSHR (0.50) TP53TSHRALDH1A1SMN1; SMN2CYP3A4
SCHEMBL5478519 0.80 TSHR (0.50) TP53TSHRALDH1A1SMN1; SMN2CYP3A4
SCHEMBL5470752 0.80 TSHR (0.50) TP53TSHRALDH1A1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462471-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2008-07-30 EP disclosed
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 EP disclosed
US-20070078256-A1 Prepolymers, prepolymer compositions, high-molecular-weight polymers with pore structure, and dielectric films DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-04-05 US disclosed
US-7186454-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-20070032556-A1 Aromatic polyamine derivative DAICEL CHEMICAL INSUSTRIES, LTD. (JP) 2007-02-08 US disclosed
US-20060241275-A1 Dielectric films and materials therefor NAGANO SHINYA 2006-10-26 US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
EP-1683822-A1 PREPOLYMER, PREPOLYMER COMPOSITION, HIGH MOLECULAR WEIGHT POLYMER HAVING STRUCTURE CONTAINING HOLE AND ELECTRICALLY INSULATING FILM Daicel Chemical Industries, Ltd. (JP) 2006-07-26 EP disclosed
EP-1681284-A1 AROMATIC POLYAMINE DERIVATIVE Daicel Chemical Industries, Ltd. (JP) 2006-07-19 EP disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 US disclosed
EP-1462471-A1 Dielectric films and materials thereof Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-20040175858-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032556-A1 Aromatic polyamine derivative SRM, PRMT1, KDM8 RXRA 1261/4885TP53 1112/4885TSHR 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.