Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 17/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084144 | 0.82 | HTT (0.44) | NTRK1IRAK4 | |
| SCHEMBL23408640 | 0.78 | PIM1 (0.40) | NTRK1IRAK4AAK1 | |
| SCHEMBL14881490 | 0.78 | IRAK4 (0.47) | NTRK1IRAK4AAK1 | |
| SCHEMBL14881458 | 0.78 | IRAK4 (0.47) | NTRK1IRAK4AAK1 | |
| SCHEMBL14896935 | 0.77 | NTRK1 (0.46) | NTRK1IRAK4 | |
| SCHEMBL21765939 | 0.77 | PDE10A (0.44) | NTRK1IRAK4AAK1 | |
| SCHEMBL14881665 | 0.77 | PIM1 (0.42) | IRAK4AAK1 | |
| SCHEMBL14882280 | 0.77 | PIM1 (0.42) | IRAK4AAK1 | |
| SCHEMBL21765944 | 0.77 | IRAK4 (0.48) | NTRK1IRAK4AAK1 | |
| SCHEMBL21765966 | 0.77 | IRAK4 (0.46) | NTRK1IRAK4AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114465-A1 | PREPARATION AND APPLICATION OF HETEROAROMATIC IMINAZOLE COMPOUND | 上海轶诺药业有限公司 | 2020-06-11 | — | — | WO | disclosed |