Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | HPGD | P15428 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | GABRP | O00591 | 3/20 | 0.70 |
| ▸ | GABRD | O14764 | 3/20 | 0.70 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.70 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.70 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.70 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.70 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.70 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.70 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.70 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.70 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.70 |
| ▸ | GABRE | P78334 | 3/20 | 0.70 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.70 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.70 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.70 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370763 | 0.85 | MEN1 (0.75) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL13259767 | 0.83 | MEN1 (1.00) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL19469987 | 0.81 | FLT3 (0.70) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL16977184 | 0.77 | MAOB (0.79) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL19470002 | 0.76 | CYP1B1 (0.71) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL26117399 | 0.73 | CYP3A4 (0.76) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL29435855 | 0.73 | CYP3A4 (0.76) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL3708991 | 0.71 | MEN1 (1.00) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL974549 | 0.70 | MAPT (0.76) | MEN1KMT2AHPGDALDH1A1GABRP | |
| SCHEMBL2905489 | 0.70 | CYP1B1 (0.72) | MEN1KMT2AHPGDALDH1A1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117988-A1 | CDK9 INHIBITORS AND POLYMORPHS THEREOF FOR USE AS AGENTS FOR TREATMENT OF CANCER | TOLERO PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |